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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Juvenile hormone epoxide hydrolase ： ウィキペディア英語版 Juvenile hormone epoxide hydrolase Juvenile hormone epoxide hydrolase (JHEH) is an enzyme that inactivates insect juvenile hormones. This inactivation is accomplished through hydrolysis of the epoxide functional group contained within these hormones into diols. JHEH is one of two enzymes involved in the termination of signaling properties of the various juvenile hormones. The other is juvenile-hormone esterase, or JH.〔 The first observation of activity from JHEH was in ''Rhodnius prolixus'' and ''Schistocerca gregaria''. JH esterase was also first observed in this same work.〔 == Mechanism == JH esterase and epoxide hydrolase are the only known enzymes involved in primary degradation of JH. The inactivated carboxylic acid products of juvenile hormone esterase can be reactivated in peripheral tissues by esterification restoring its biological activity. In contrast, the juvenile hormone diols that are the product of the epoxide hydrolase are very hydrophilic and cannot be converted back to JH. Thus, this enzyme permantly terminates the action of juvenile hormone, unlike JH esterase. The enzyme mechanism involves the addition of water at the secondaary carbon, C-10. In ''Trichoplusia ni'', JH has been found to be the preferred substrate of this enzyme as compared with JH acid. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Juvenile hormone epoxide hydrolase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.